The Comparison of Maceration And Soxhacletation Methods Effectiveness on Garlic Extract to Inhibit Staphylococus Aureus Growth

Introduction: An abscess is pathological, pus-filled cavity caused by mixed bacterial infection. Bacteria that a role in the process, namely Staphyloccocus aureus. Treatment of abscesses is usually by antibiotics. Abscesses caused by Staphylococcus aureus appears to be resistant to antibiotics, alternative needed by utilizing herbal plants such as garlic. Garlic has active ingredient allicin has antibacterial. Objective: The purpose was to determined which method was the most effective among maceration and soxhletation methods in making garlic extract with a concentration of 50% against the resistance of Staphyloccocus aureus. Material and Methods: The research method used Kirby Bauer method which is sensitivity test with the agar diffusion method using the disc diffusion technique. The Kirby Bauer sensitivity test using selective media, namely Muller Hinton Agar media, the inhibition zone is created area with a clear zone around the disc. Result: Data obtained from the results this study were statistically tested using normality with Shapiro-Wilk to see whether the data normally distributed or not, the expression was with the One Way Anova test to see whether there was a difference that could be measured later with the Least Significant Difference test to see groups that are influential in inhibiting bacteria. Discussion: The content of active compounds from garlic extract by soxhletation method more easily extracted because circulation that can increase the rate of transfer compounds from extract. Conclusion: The results, 50% concentration of garlic extract using the soxhletation more effective in inhibiting the growth of Staphylococcus aureus bacteria than the maceration method.