PENGARUH PEMBERIAN SALEP EKSTRAK DAUN BINAHONG (ANREDERA CORDIFOLA (TEN.) STEENIS) TERHADAP PENINGKATAN JUMLAH SEL FIBROBLAS PADA PENYEMBUHAN LUKA PASCA INSISI MENCIT (MUS MUSCULUS)

Anredera cordifolia is a potential medicinal plant that can cure disease. Theleaves (Anredera cordifolia (Ten.) steenes) have such properties as accelerating therecovery of health after surgery, healing of various wounds, both internal andexternal injuries, inflammation of the intestines, initiating blood circulation,preventing stroke, stomach, uric acid, restoring the vitality of the body resistance,as well as diabetes. Beetle leaves contain active compounds of flavonoids, alkaloids,terpenoids, and saponins. The aim of this study is to find out at what concentrationthere is an increase in the number of fibroblast cells at the time of applying theointment extract leaf (Anredera cordifolia (Ten.) steenis) for healing post insectionscratch wounds (Mus musculus). The method used in this study is experimentallaboratory in vivo with post test only control group design. The results of this studyshowed that the concentration of pineapple leaf extract ointment against the numberof fibroblast cells in the healing of post-inscription wounds suggested that 30%,35%, and 40% pineal leaf extracts ointments can increase the percentage of theamount of fibroblases in the wound healing process