Recurrent Case of Herpetic Stromal Keratitis: How to Management

Herpetic stromal keratitis (HSK) is a disease of the cornea initiated by infection with herpes simplex virus type 1 (HSV-1) with T cell-mediated pathology.1 The virus can be spread through direct contact with body fluids such as saliva, mucus, or fluid from active lesions on the skin or mucosa.2 The disease is characterized by corneal stromal involvement, increased corneal opacities and visual impairment. Damage to corneal tissue is mainly caused by the accumulation of neutrophils and CD4 T cells in the inflamed cornea, leading to the development of severe HSK.3 HSK infections in developed countries are estimated to be 10 30 per 100,000 population per year, with higher rates in developing countries. In low-income countries, HSK accounts for a significant number of blindness cases compared to other infectious eye diseases